Publications

Beachum AN*, Salazar G*, Nachbar A, Krause K, Klose H, Meyer K, Maserejian A, Ross G, Boyd H, Weigel T, Ambaye L, Miller H, and Coutinho-Budd J. (2024) Glia multitask to compensate for neighboring glial dysfunction. BioRxiv, doi: 10.1101/2024.09.06.711719
*co-first author

Coutinho-Budd J*, Freeman MR, Ackerman, S* (2024). Glial regulation of circuit wiring, firing, and expiring in the Drosophila Central Nervous System. Cold Spring Harb Perspect Biol, a041347. doi: 10.1101/cshperspect.a041347
*co-corresponding authors

Jindal, DA, Leier HC, Salazar G, Foden AJ, Seitz EA, Wilkov AJ, Coutinho-Budd J*, and Broihier HT*. (2023) Early Draper-mediated glial refinement of neuropil architecture and synapse number in the Drosophila antennal lobe. Front Cell Neurosci 17:1166199
*co-corresponding authors

Corty M and Coutinho-Budd J. (2023) Drosophila glia take shape to sculpt the nervous system. Curr Op in Neurobiol, 79:102689. (Review)

Hermann K, Liu Y, Llobet-Rosell A, McLaughlin CN, Neukomm L, Coutinho-Budd J, and Broihier H. (2022) Divergent signaling requirements of dSARM in injury-induced degeneration and developmental glial phagocytosis. PLOS Genetics, 18(6):e1010257

Salazar G, Ross G, Maserejian AE, and Coutinho-Budd J. (2022) Quantifying glial-glial tiling using automated image analysis in Drosophila. Front Cell Neuroscience, 16:826483.

Coutinho-Budd J and Broihier HT. (2020) Pyroptosis takes aim at neurodevelopment. Dev Cell 53, 498-499. Spotlight.

McLaughlin CN, Perry-Richardson J, Coutinho-Budd J, and Broihier H. (2019) Dying neurons utilize innate immune signaling to prime glia for phagocytosis during development. Dev Cell 48, 506-522.

Coutinho-Budd J. (2018) Adapting to barriers: glial septate junctions stretch to keep up. Dev Cell 47, 688-689. Preview.

Cho S, Muthukumar A, Stork T, Coutinho-Budd J, and Freeman M. (2018) Focal Adhesion molecules regulate astrocyte morphology and glutamate transporters to suppress seizure-like behavior. PNAS 115, 11316-11321.

Coutinho-Budd J, Sheehan A, and Freeman M. (2017) The secreted neurotrophin Spätzle3 promotes glial morphogenesis and supports neuronal survival and function. Genes Dev 31, 2023–2038.

Neukomm LJ, Burdett TC, Seeds AM, Hampel S, Coutinho-Budd JC, Farley JE, Wong J, Karadeniz Y, Osterloh JM, Sheehan AE, and Freeman MR (2017) Axon death pathways converge on Axundead to promote functional and structural axon disassembly. Neuron 95, 78-91.

Coutinho-Budd J and Freeman M. (2013) Probing the enigma: unraveling glial cell biology in invertebrates. Curr Op in Neurobiol 23, 1073-1079. (Review)

Coutinho-Budd JC, Snider SB, Fitzpatrick BJ, Rittiner JE, and Zylka MJ. (2013) Biological constraints limit the use of rapamycin-inducible FKBP12-Inp54p for depleting PIP2 in dorsal root ganglia neurons. JNRBM12, e13.

Kokel D, Cheung CY, Mills R, Coutinho-Budd J, Huang L, Setola V, Sprague J, Jin S, Jin Y, Huang X-P, Bruni G, Woolf C, Roth B, Hamblin M, Zylka N, Milan M & Peterson R.(2013) Photochemical activation of TRPA1 channels in neurons and animals. Nat Chem Biol 9, 257-263.

Bank L, Bianchi L, Ebisu F, Lerman-Sinkoff D, Smiley E, Shen Y, Ramamurthy P, Thompson D, Roth T, Beck C, Flynn M, Teller R, Feng L, Llewellyn GN, Holmes B, Sharples C, Coutinho-Budd J, Linn S, Chervenak A, Dolan D, Benson J, Kanicki A, Martin C, Altschuler R, Koch A, Jewett E, Germiller J and Barald K. (2012) The cytokine, Macrophage Migration Inhibitory Factor (MIF) acts as a neurotrophin for neurons in the developing mammalian and avian inner ears. Development 139, 4666-4674.

Coutinho-Budd J, Ghukasyan V, Zylka M, and Polleux F. (2012) The F-BAR domains from srGAP1, srGAP2, and srGAP3 differentially regulate membrane deformation. J Cell Sci 125, 3390-3401.

Charrier C, Joshi K, Coutinho-Budd J, Kim J-E, Lambert N, de Marchena Powell J, Jin W-L, Vanderhaeghen P, Ghosh A, Sassa T, and Polleux F. (2012) Inhibition of srGAP2 function in dendritic spine maturation by its human-specific paralogs. Cell 149, 923-35.

Guerrier S, Coutinho-Budd J, Sassa T, Gresset A, Vincent Jordan N, Chen K, Jin W-L, Frost A, and Polleux F. (2009) srGAP2 regulates neuronal migration and morphogenesis through the ability of its F-BAR domain to induce membrane protrusions. Cell 138, 990-1004

Coutinho-Budd J, Ezerman E and Forehand C. (2008) The effect of cAMP signaling on the longitudinal extension of spinal sensory neurons in the chicken embryo. J. Anat. 213, 547–554